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Testing the Antigenotoxicity and Anticytotoxicity Properties of Prunella Grandiflora L. Extract Using the Example of Drosophila Melanogaster

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Заглавие Testing the Antigenotoxicity and Anticytotoxicity Properties of Prunella Grandiflora L. Extract Using the Example of Drosophila Melanogaster
 
Автор Magombe, N.
Kostenko, V. V.
Antosyuk, O. N.
Bolotnik, E. V.
 
Тематика EXTRACT
PRUNELLA
ETOPOSIDE
MORPHOMETRY
ANTIGENOTOXIC
 
Описание Received: 05.04.2022. Revised: 21.07.2022. Accepted: 25.07.2022. Available online: 08.08.2022.
This paper belongs to the MOSM2021 Special Issue.
Using the Drosophila melanogaster model object, the presence of protective properties in 10% of Prunella grandiflora L. (Lamiaceae) extract was determined in relation to the toxic and cytotoxic effects of the antitumor drug etoposide in two concentrations of 800 and 8000 μg/kg of nutrient medium. The grass P. grandiflora was collected in the flowering phase in Sverdlovsk region (N 56°09'22.0'', E 058°32'19.6'') in 2021. No genotoxic manifestations of the extract were found. Comparative characteristics of wing parameters under the influence of etoposide at a dose of 800 and 8000 g showed significant differences in linear and two-dimensional parameters of the wing.
This work was financially supported by Decree No. 211 of the Government of the Russian Federation, contract No. 02.A03.21.0006.
 
Дата 2022-08-24T07:18:45Z
2022-08-24T07:18:45Z
2022-07
 
Тип Article
Journal article (info:eu-repo/semantics/article)
Published version (info:eu-repo/semantics/publishedVersion)
 
Идентификатор Testing the Antigenotoxicity and Anticytotoxicity Properties of Prunella Grandiflora L. Extract Using the Example of Drosophila Melanogaster / Ngonidzaishe Magombe, V. V. Kostenko, O. N. Antosyuk, E. V. Bolotnik // Chimica Techno Acta. — 2022. — Vol. 9, Supplement: MOSM 2021 Special Issue. — No. 202292S14.
2411-1414
http://elar.urfu.ru/handle/10995/116470
https://www.elibrary.ru/item.asp?id=49334087
10.15826/chimtech.2022.9.2.S14
 
Язык en
 
Связанные ресурсы Chimica Techno Acta. 2022. Vol. 9. Supplement
 
Формат application/pdf
 
Издатель Ural Federal University
Уральский федеральный университет