Ceramic Materials Based on Lanthanum Zirconate for the Bone Augmentation Purposes: Cytocompatibility in a Cell Culture Model
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Ceramic Materials Based on Lanthanum Zirconate for the Bone Augmentation Purposes: Cytocompatibility in a Cell Culture Model
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| Автор |
Ulitko, M. V.
Antonets, Yu. Antropova, I. P. Mullabaev, A. R. Volokitina, E. A. Kasyanova, A. V. Loginova, E. Tarasova, N. A. |
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| Тематика |
LANTHANUM ZIRCONATE
BIOCERAMICS OSTEOREPLACEMENT MATERIAL CYTOCOMPATIBILITY CELL CULTURE |
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| Описание |
During the interaction with the studied materials, the human cell viability is sufficient to maintain their regenerative potential.
Doping of La2Zr2O7 with Ca or Sr slowing down the adaptation of human fibroblasts to the ceramic material. Sr, Zr and La were found in the culture medium, which did not affect cytocompatibility during the cultivation period. Received: 03.08.23. Revised: 11.08.23. Accepted: 14.08.23. Available online: 16.08.23. Creation of new ceramic materials for the bone augmentation purposes that combine the absence of cytotoxicity, high strength and osseointegration characteristics is an urgent modern task. In this work, the cytocompatibility of ceramic materials based on lanthanum zirconate (La2Zr2O7) was determined to assess the prospects for their use as implants and components of human joint endoprostheses. The effect of ceramic materials based on undoped and alkali-earth (Ca, Sr) doped La2Zr2O7 on the viability and proliferative activity of human cells was evaluated. The release of elements into the culture medium was also evaluated. This work was supported by the Russian Science Foundation (grant no. 22-25-20037), https://www.rscf.ru/en. |
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| Дата |
2024-01-18T12:45:24Z
2024-01-18T12:45:24Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) Published version (info:eu-repo/semantics/publishedVersion) |
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| Идентификатор |
Ceramic Materials Based on Lanthanum Zirconate for the Bone Augmentation Purposes: Cytocompatibility in a Cell Culture Model / M. V. Ulitko, Yu. Antonets, I. P. Antropova, A. R. Mullabaev, E. A. Volokitina, A. V. Kasyanova, E. Loginova, N. A. Tarasova // Chimica Techno Acta. — 2023. — Vol. 10, No. 4. — № 202310402.
2411-1414 http://elar.urfu.ru/handle/10995/129340 https://www.elibrary.ru/item.asp?id=60040539 10.15826/chimtech.2023.10.4.02 |
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| Язык |
en
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| Связанные ресурсы |
Chimica Techno Acta. 2023. Vol. 10. № 4
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| Формат |
application/pdf
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| Издатель |
Уральский федеральный университет
Ural Federal University |
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