Modification of Bacterial Cellulose Using Silk Fibroin β-sheet Crystals Induced by Ultrasonication
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Modification of Bacterial Cellulose Using Silk Fibroin β-sheet Crystals Induced by Ultrasonication
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| Автор |
Carranza, M. S.
Bascos, N. A. D. Tan, M. C. Franco, F. Jr |
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| Тематика |
SILK FIBROIN
Β-SHEET CRYSTALS BACTERIAL CELLULOSE COMPOSITE |
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| Описание |
Received: 11.01.24. Revised: 30.01.24. Accepted: 30.01.24. Available online: 05.02.24.
The authors would like to acknowledge the contributions of Mr. John Paulin, Mr. Bernard, Ms. Patricia Palomillo, and Mr. Robert Jervine Ortega. We would also like to acknowledge Sigmatech PH for allowing us to run our samples during our visit to their facility. Ultrasonication of regenerated SF absorbed by BC hydrogels allowed for entrapment of a mixture of silk I- and silk II-dominant structured proteins. Beta-sheet crystals formed allowed for a more thermodynamically stable double-network hydrogel. Ultrasonication of BC-SF composites is a facile and novel method for developing biomaterial applications. Silk fibroin (SF) has been continuously explored as a biomaterial due to its biocompatibility, tunability, and self-healing properties. In this work, we present a novel approach to the modification of bacterial cellulose (BC) with SF β-sheet dominant structures induced via ultrasonication. Secondary structure analysis through infrared spectroscopy, thioflavin T assay, and circular dichroism spectropolarimetry revealed a conversion of silk I to silk II structures within the protein mixture. Cold field emission scanning electron microscope images revealed the tightly packed fibers coated with the protein. Thermogravimetric curves demonstrated higher resistance to temperature degradation supplemented by broader and flatter DSC curves attributed to the highly bonded and dense composite. Successful conversion of amide I to amide II and amide III allowed for the more stable β-crystals to contribute to a more thermodynamically stable doublenetwork hydrogel. The conversion of silk I to silk II structures offers a viable and highly biocompatible material that is both thermodynamically and biochemically stable for various potential biomedical applications. The authors want to acknowledge funding from the Research & Grants Management Office (RGMO) of De La Salle University – Manila (Project number: 16 FU1TAY20-1TAY22). |
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| Дата |
2024-04-04T11:26:09Z
2024-04-04T11:26:09Z 2024 |
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| Тип |
Article
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| Идентификатор |
Modification of Bacterial Cellulose Using Silk Fibroin β-sheet Crystals Induced by Ultrasonication / Mary Stephanie Carranza, Neil Andrew D. Bascos, Maria Carmen Tan, Francisco Franco Jr. // Chimica Techno Acta. — 2024. — Vol. 11, No. 1. — No. 202411107.
2411-1414 http://elar.urfu.ru/handle/10995/130178 https://elibrary.ru/item.asp?id=65118506 10.15826/chimtech.2024.11.1.07 |
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| Язык |
en
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| Связанные ресурсы |
Chimica Techno Acta. 2024. Vol. 11. № 1
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| Издатель |
Уральский федеральный университет
Ural Federal University |
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