The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones
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| Автор |
Viktorova, V. V.
Steparuk, E. V. Obydennov, D. L. Sosnovskikh, V. Y. |
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| Тематика |
4-PYRIDONE
ALDEHYDE-LACTOL TAUTOMERISM AMMONIUM ACETATE BENZIMIDAZOLE OXAZINONE RING-OPENING |
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| Описание |
This work describes the synthesis of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones, their tautomerism, and reactivity towards binucleophiles. These molecules are novel and convenient building-blocks for the direct construction of biologically important polycyclic pyridones via an oxazinone ring-opening transformation promoted with ammonium acetate or acetic acid. In the case of o-phenylenediamine, partial aromatization of the obtained heterocycles proceeded to form polycyclic benzimidazole-fused pyridones (33–91%). © 2023 by the authors.
Ministry of Education and Science of the Russian Federation, Minobrnauka The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program) is gratefully acknowledged. |
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| Дата |
2024-04-05T16:15:24Z
2024-04-05T16:15:24Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Viktorova, VV, Steparuk, EV, Obydennov, DL & Sosnovskikh, VY 2023, 'The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones', Molecules, Том. 28, № 3, 1285. https://doi.org/10.3390/molecules28031285
Viktorova, V. V., Steparuk, E. V., Obydennov, D. L., & Sosnovskikh, V. Y. (2023). The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones. Molecules, 28(3), [1285]. https://doi.org/10.3390/molecules28031285 1420-3049 Final All Open Access, Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147893723&doi=10.3390%2fmolecules28031285&partnerID=40&md5=b19e77a9b31090321552940eaca0a5e5 https://www.mdpi.com/1420-3049/28/3/1285/pdf?version=1674910466 http://elar.urfu.ru/handle/10995/130197 10.3390/molecules28031285 85147893723 000933749700001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
MDPI
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| Источник |
Molecules
Molecules |
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