Fear memory in humans is consolidated over time independently of sleep
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Fear memory in humans is consolidated over time independently of sleep
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| Автор |
Pavlov, Y. G.
Pavlova, N. V. Diekelmann, S. Kotchoubey, B. |
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| Тематика |
EEG
EVENT-RELATED POTENTIALS FEAR CONDITIONING SLEEP BRAIN CONDITIONED REFLEX FEAR HUMAN PHYSIOLOGY REINFORCEMENT (PSYCHOLOGY) SLEEP BRAIN CONDITIONING, CLASSICAL EXTINCTION, PSYCHOLOGICAL FEAR HUMANS SLEEP |
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| Описание |
Fear memories can be altered after acquisition by processes, such as fear memory consolidation or fear extinction, even without further exposure to the fear-eliciting stimuli, but factors contributing to these processes are not well understood. Sleep is known to consolidate, strengthen, and change newly acquired declarative and procedural memories. However, evidence on the role of time and sleep in the consolidation of fear memories is inconclusive. We used highly sensitive electrophysiological measures to examine the development of fear-conditioned responses over time and sleep in humans. We assessed event-related brain potentials (ERP) in 18 healthy, young individuals during fear conditioning before and after a 2-hour afternoon nap or a corresponding wake interval in a counterbalanced within-subject design. The procedure involved pairing a neutral tone (CS+) with a highly unpleasant sound. As a control, another neutral tone (CS−) was paired with a neutral sound. Fear responses were examined before the interval during a habituation phase and an acquisition phase as well as after the interval during an extinction phase and a reacquisition phase. Differential fear conditioning during acquisition was evidenced by a more negative slow ERP component (stimulus-preceding negativity) developing before the unconditioned stimulus (loud noise). This differential fear response was even stronger after the interval during reacquisition compared with initial acquisition, but this effect was similarly pronounced after sleep and wakefulness. These findings suggest that fear memories are consolidated over time, with this effect being independent of intervening sleep. © 2022, The Author(s).
Deutsche Forschungsgemeinschaft, DFG: KO-1753/13-4 The study was supported by the German Research Society (Deutsche Forschungsgemeinschaft, DFG), grant KO-1753/13-4. The authors thank Martin King, Marina Zimmermann, and Nina Heidemann for their help with data collection. |
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| Дата |
2024-04-05T16:16:51Z
2024-04-05T16:16:51Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Pavlov, YG, Pavlova, NV, Diekelmann, S & Kotchoubey, B 2023, 'Fear memory in humans is consolidated over time independently of sleep', Cognitive, Affective, & Behavioral Neuroscience, Том. 23, № 1, стр. 100-113. https://doi.org/10.3758/s13415-022-01037-5
Pavlov, Y. G., Pavlova, N. V., Diekelmann, S., & Kotchoubey, B. (2023). Fear memory in humans is consolidated over time independently of sleep. Cognitive, Affective, & Behavioral Neuroscience, 23(1), 100-113. https://doi.org/10.3758/s13415-022-01037-5 1530-7026 Final All Open Access, Hybrid Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140079222&doi=10.3758%2fs13415-022-01037-5&partnerID=40&md5=4597eb6431a27b8697c09fc71faa5b81 https://link.springer.com/content/pdf/10.3758/s13415-022-01037-5.pdf http://elar.urfu.ru/handle/10995/130248 10.3758/s13415-022-01037-5 85140079222 000873967200001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
Springer
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| Источник |
Cognitive, Affective, & Behavioral Neuroscience
Cognitive, Affective and Behavioral Neuroscience |
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