Out of Asia? Expansion of Eurasian Lyme borreliosis causing genospecies display unique evolutionary trajectories
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
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Out of Asia? Expansion of Eurasian Lyme borreliosis causing genospecies display unique evolutionary trajectories
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| Автор |
Rollins, R. E.
Sato, K. Nakao, M. Tawfeeq, M. T. Herrera-Mesías, F. Pereira, R. J. Kovalev, S. Margos, G. Fingerle, V. Kawabata, H. Becker, N. S. |
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| Тематика |
BORRELIA BURGDORFERI
GEOGRAPHIC EXPANSION LYME BORRELIOSIS NICHE PATHOGEN EVOLUTION VECTOR ADAPTATION ANIMAL ASIA BORRELIA BORRELIELLA GENETICS HUMAN IXODES LYME DISEASE MICROBIOLOGY PHYSIOLOGY RODENT ANIMALS ASIA BORRELIA BORRELIA BURGDORFERI GROUP HUMANS IXODES LYME DISEASE RODENTIA |
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| Описание |
Vector-borne pathogens exist in obligate transmission cycles between vector and reservoir host species. Host and vector shifts can lead to geographic expansion of infectious agents and the emergence of new diseases in susceptible individuals. Three bacterial genospecies (Borrelia afzelii, Borrelia bavariensis, and Borrelia garinii) predominantly utilize two distinct tick species as vectors in Asia (Ixodes persulcatus) and Europe (Ixodes ricinus). Through these vectors, the bacteria can infect various vertebrate groups (e.g., rodents, birds) including humans where they cause Lyme borreliosis, the most common vector-borne disease in the Northern hemisphere. Yet, how and in which order the three Borrelia genospecies colonized each continent remains unclear including the evolutionary consequences of this geographic expansion. Here, by reconstructing the evolutionary history of 142 Eurasian isolates, we found evidence that the ancestors of each of the three genospecies probably have an Asian origin. Even so, each genospecies studied displayed a unique substructuring and evolutionary response to the colonization of Europe. The pattern of allele sharing between continents is consistent with the dispersal rate of the respective vertebrate hosts, supporting the concept that adaptation of Borrelia genospecies to the host is important for pathogen dispersal. Our results highlight that Eurasian Lyme borreliosis agents are all capable of geographic expansion with host association influencing their dispersal; further displaying the importance of host and vector association to the geographic expansion of vector-borne pathogens and potentially conditioning their capacity as emergent pathogens. © 2022 The Authors. Molecular Ecology published by John Wiley & Sons Ltd.
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES; Liaoning Medical University, LMU; Norges Forskningsråd; South East Regional Health Authority, SERHA; Graduate School of Life Sciences, Julius-Maximilians-Universität Würzburg, GSLS; Max-Planck-Instituts für Ornithologie, MPIO The Pacific Bioscience SMRT sequencing service was provided by the Norwegian Sequencing Centre (www.sequencing.uio.no), a national technology platform hosted by the University of Oslo and supported by the “Functional Genomics” and “Infrastructure” programmes of the Research Council of Norway and the South-eastern Regional Health Authorities. We would further like to thank Dr Kristian Ullrich for his support in bioinformatic analyses. We would like to thank all past members of the Evolutionary Biology group at the LMU, all laboratory technicians and colleagues at the National Reference Centre for Borrelia, the National Institute of Infection Diseases in Tokyo for allowing us to work in their facilities, all members of the Evolutionary Ecology of Variation group of the Max Plank Institute for Ornithology and the Behavioural Ecology group at LMU for allowing us to collect ticks in their study plots. This work was done in association with the Graduate School of Life Science, Munich. Open Access funding enabled and organized by Projekt DEAL. We are grateful to the Federal University of Juiz de Fora (UFJF). This study was financed by the Coordination of Improvement of Higher Education Personnel - Brazil (CAPES) - Finance Code 001. |
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| Дата |
2024-04-05T16:19:40Z
2024-04-05T16:19:40Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Rollins, RE, Sato, K, Nakao, M, Tawfeeq, MT, Herrera‐mesías, F, Pereira, RJ, Kovalev, S, Margos, G, Fingerle, V, Kawabata, H & Becker, NS 2023, 'Out of Asia? Expansion of Eurasian Lyme borreliosis causing genospecies display unique evolutionary trajectories', Molecular Ecology, Том. 32, № 4, стр. 786-799. https://doi.org/10.1111/mec.16805
Rollins, R. E., Sato, K., Nakao, M., Tawfeeq, M. T., Herrera‐mesías, F., Pereira, R. J., Kovalev, S., Margos, G., Fingerle, V., Kawabata, H., & Becker, N. S. (2023). Out of Asia? Expansion of Eurasian Lyme borreliosis causing genospecies display unique evolutionary trajectories. Molecular Ecology, 32(4), 786-799. https://doi.org/10.1111/mec.16805 0962-1083 Final All Open Access, Hybrid Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144133379&doi=10.1111%2fmec.16805&partnerID=40&md5=238e31ba775745a06562ca283c2b74db https://doi.org/10.1111/mec.16805 http://elar.urfu.ru/handle/10995/130392 10.1111/mec.16805 85144133379 000898998700001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by-nc https://creativecommons.org/licenses/by-nc/4.0/ |
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| Формат |
application/pdf
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| Издатель |
John Wiley and Sons Inc
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| Источник |
Molecular Ecology
Molecular Ecology |
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