THE MORPHOLOGICAL AND MORPHOMETRIC STUDY OF THE SCIATIC NERVE AFTER AMPUTATION AND PROSTHETICS OF THE LEG EXPERIMENTALLY USING AN ORIGINAL IMPLANT
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| Заглавие |
THE MORPHOLOGICAL AND MORPHOMETRIC STUDY OF THE SCIATIC NERVE AFTER AMPUTATION AND PROSTHETICS OF THE LEG EXPERIMENTALLY USING AN ORIGINAL IMPLANT
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| Автор |
Varsegova, T. N.
Emanov, A. A. Kuznetsov, V. P. Ovchinnikov, E. N. |
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| Тематика |
AMPUTATION
IMPLANT LEG MORPHOLOGY MORPHOMETRY SCIATIC NERVE AMPUTATION ANIMAL EXPERIMENT ANIMAL MODEL ARTICLE DOG MORPHOLOGY MORPHOMETRY NERVE STUMP NONHUMAN PREVALENCE SCIATIC NERVE TIBIA OSTEOTOMY |
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| Описание |
Purpose of the Study was to identify the morphological and morphometric changes in the sciatic nerve after amputation and prosthetics of the leg with an original implant experimentally. Six dogs had underwent the tibia osteotomy at the border of the upper and middle thirds, and an implant of PressFit type was driven in. The stump was modeled. The fixation of the bone and compression load on the bone (Fl=20N) was performed with a special device. The sciatic nerves were studied 180 days after prosthetics. Sciatic nerves of 5 intact dogs were control. About 6.39 % of myelin fibers demonstrated signs of myelin and axon damage. The number of myelin fibers increased 1.81-fold with 2.05-fold decrease in axon diameter, 3.52-fold decrease – in myelin thickness (p=0.000) and with loss of large myelin fibers with a diameter of more than 10 microns. The number of non-myelinated fibers increased 4.23-fold (p=0.000). The retrograde changes revealed in the sciatic nerve in the form of neuropraxia and axonotmesis, loss of large myelin fibers and regenerative processes may be one of the causes of post-amputation pain syndrome. © 2023 Stavropol State Medical University. All rights reserved.
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| Дата |
2024-04-05T16:20:38Z
2024-04-05T16:20:38Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Варсегова, ТН, Еманов, АА, Кузнецов, ВП & Овчинников, ЕН 2023, 'МОРФОЛОГИЧЕСКОЕ И МОРФОМЕТРИЧЕСКОЕ ИССЛЕДОВАНИЕ СЕДАЛИЩНОГО НЕРВА ПОСЛЕ АМПУТАЦИИ И ПРОТЕЗИРОВАНИЯ ГОЛЕНИ ОРИГИНАЛЬНЫМ ИМПЛАНТАТОМ В ЭКСПЕРИМЕНТЕ', Медицинский вестник Северного Кавказа, Том. 18, № 1, стр. 50-54. https://doi.org/10.14300/mnnc.2023.18012
Варсегова, Т. Н., Еманов, А. А., Кузнецов, В. П., & Овчинников, Е. Н. (2023). МОРФОЛОГИЧЕСКОЕ И МОРФОМЕТРИЧЕСКОЕ ИССЛЕДОВАНИЕ СЕДАЛИЩНОГО НЕРВА ПОСЛЕ АМПУТАЦИИ И ПРОТЕЗИРОВАНИЯ ГОЛЕНИ ОРИГИНАЛЬНЫМ ИМПЛАНТАТОМ В ЭКСПЕРИМЕНТЕ. Медицинский вестник Северного Кавказа, 18(1), 50-54. https://doi.org/10.14300/mnnc.2023.18012 2073-8137 Final All Open Access, Bronze https://www.scopus.com/inward/record.uri?eid=2-s2.0-85154559590&doi=10.14300%2fMNNC.2023.18012&partnerID=40&md5=6dde0e99c5f8dab4382302f2c8bc26be https://medvestnik.stgmu.ru/files/articles/1362.pdf http://elar.urfu.ru/handle/10995/130439 50463631 10.14300/MNNC.2023.18012 85154559590 |
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| Язык |
ru
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| Права |
Open access (info:eu-repo/semantics/openAccess)
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| Формат |
application/pdf
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| Издатель |
Stavropol State Medical University
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| Источник |
Medical news of the North Caucasus
Medical News of North Caucasus |
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