Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels
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| Автор |
Starodumov, I.
Makhaeva, K. Zubarev, A. Bessonov, I. Sokolov, S. Mikushin, P. Alexandrov, D. Chestukhin, V. Blyakhman, F. |
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| Тематика |
CFL
COMPUTER MODELING ERYTHROCYTES HEMODYNAMICS MULTICOMPONENT FLOW |
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| Описание |
This mainly theoretical work is devoted to the study of the contribution of the cell-free layer (CFL) near the vessel wall to hemodynamics in a large coronary artery with stenosis to assess the relevance of CFL modeling to the needs of interventional cardiology. An Euler–Euler model considering blood as a two-component fluid with a discrete phase of erythrocytes and a liquid plasma phase was applied to a simple 2d vessel with 65% stenosis. It was found that both the CFL thickness and the local contribution of the CFL thickness to hemodynamics are inhomogeneous along the vessel. The effects of CFL on the velocity profiles, vortex formation, hematocrit, viscosity, and wall shear stresses in the area of stenosis were determined. To demonstrate the significance of CFL modeling for prognostic purposes, the same hemodynamic conditions, analyzed using a one-component model, were also considered. A comparison analysis showed that the existence of CFL resulted in a significant overestimation (up to over 100%) of the main hemodynamic characteristics of the flow obtained using the model based on the Carreau equation. © 2023 by the authors.
Russian Science Foundation, RSF: 22-71-10071 This study was supported by the Russian Science Foundation (project no. 22-71-10071). |
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| Дата |
2024-04-05T16:31:57Z
2024-04-05T16:31:57Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Starodumov, I, Makhaeva, K, Zubarev, A, Bessonov, I, Sokolov, S, Mikushin, P, Alexandrov, D, Chestukhin, V & Blyakhman, F 2023, 'Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels', Fluids, Том. 8, № 8, 230. https://doi.org/10.3390/fluids8080230
Starodumov, I., Makhaeva, K., Zubarev, A., Bessonov, I., Sokolov, S., Mikushin, P., Alexandrov, D., Chestukhin, V., & Blyakhman, F. (2023). Modeling of Local Hematocrit for Blood Flow in Stenotic Coronary Vessels. Fluids, 8(8), [230]. https://doi.org/10.3390/fluids8080230 2311-5521 Final All Open Access, Gold https://www.scopus.com/inward/record.uri?eid=2-s2.0-85169052242&doi=10.3390%2ffluids8080230&partnerID=40&md5=a129df8a2767a0adaf9da0e3040f3995 https://www.mdpi.com/2311-5521/8/8/230/pdf?version=1692338006 http://elar.urfu.ru/handle/10995/130746 10.3390/fluids8080230 85169052242 001057357300001 |
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| Язык |
en
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| Связанные ресурсы |
info:eu-repo/grantAgreement/RSF//22-71-10071
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
Multidisciplinary Digital Publishing Institute (MDPI)
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| Источник |
Fluids
Fluids |
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