Kinetic Potentiometry as a Method for Studying the Interactions of Antioxidants with Peroxyl Radicals
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Kinetic Potentiometry as a Method for Studying the Interactions of Antioxidants with Peroxyl Radicals
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| Автор |
Gerasimova, E.
Salimgareeva, E. Magasumova, D. Ivanova, A. |
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| Тематика |
ANTIRADICAL CAPACITY
INHIBITOR KINETIC POTENTIOMETRY PEROXYL RADICALS RATE CONSTANT |
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| Описание |
This work presents a new method using kinetic potentiometry to study the thermodynamic and kinetic parameters of the reactions of antioxidants with peroxyl radicals. The rate constants of the reaction of antioxidants with radicals have been determined, and the groups of “fast” and “slow” antioxidants have been conventionally distinguished. Fast antioxidants include ascorbic, uric, gallic, chlorogenic, caffeic acids, glutathione, L-cysteine, and catechol with constant values from (1.05–9.25) × 103 M·s−1; “slow” antioxidants are α-tocopherol (in aqueous media), ionol, 2,6-ditretbutylphenol, and compounds of the azoloazine series, modified with polyphenolic fragments, with constant values from (4.00–8.50) × 102 M·s−1. It is shown that the value of the rate constant is directly related to the type of kinetic dependence of the potential recorded when an antioxidant is introduced into the solution of the radical initiator. It is shown that the method with the determination of the induction period is difficult in the study of “slow” antioxidants. It has been established that the area above the curve of the kinetic dependence Exp(∆E) is directly related to the amount of inhibited peroxyl radicals and can be used to assess the inhibitory properties of an antioxidant from a thermodynamic point of view. “Fixed time method” and “Initial rate method” were used. Positive correlations between the described method have been established. The utility of the parameter of the area above the curve of the kinetic dependence Exp(∆E) in the study of objects of complex composition is shown. © 2023 by the authors.
Ministry of Education and Science of the Russian Federation, Minobrnauka: 075-15-2023-373 The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program) is gratefully acknowledged (No. 075-15-2023-373 from 20 February 2023). |
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| Дата |
2024-04-05T16:32:04Z
2024-04-05T16:32:04Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Gerasimova, E, Salimgareeva, E, Magasumova, D & Ivanova, A 2023, 'Kinetic Potentiometry as a Method for Studying the Interactions of Antioxidants with Peroxyl Radicals', Antioxidants, Том. 12, № 8, 1608. https://doi.org/10.3390/antiox12081608
Gerasimova, E., Salimgareeva, E., Magasumova, D., & Ivanova, A. (2023). Kinetic Potentiometry as a Method for Studying the Interactions of Antioxidants with Peroxyl Radicals. Antioxidants, 12(8), [1608]. https://doi.org/10.3390/antiox12081608 2076-3921 Final All Open Access, Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85169100122&doi=10.3390%2fantiox12081608&partnerID=40&md5=a145fdd836e2adfbe61f4f08e4924494 https://www.mdpi.com/2076-3921/12/8/1608/pdf?version=1692004653 http://elar.urfu.ru/handle/10995/130750 10.3390/antiox12081608 85169100122 001056831800001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
Multidisciplinary Digital Publishing Institute (MDPI)
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| Источник |
Antioxidants
Antioxidants |
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