Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones
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| Автор |
Aluru, R.
Mukherjee, A. Zyryanov, G. V. Majee, A. Santra, S. |
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| Тематика |
ANTIDIABETIC
AURONES CHALCONE FLAVONOIDS Α-GLUCOSIDASE INHIBITOR AMYLASE ANTIDIABETIC AGENT AURONE CHALCONE DERIVATIVE ETHYLENE OXIDE DERIVATIVE FLAVANOID FLAVONE DERIVATIVE GLUCOSIDASE NATURAL PRODUCT PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA UNCLASSIFIED DRUG ANNULATION REACTION ANTIDIABETIC ACTIVITY ANTIINFLAMMATORY ACTIVITY ANTIMICROBIAL ACTIVITY ANTINEOPLASTIC ACTIVITY ANTIOXIDANT ACTIVITY ANTIVIRAL ACTIVITY BIOLOGICAL ACTIVITY BIOSYNTHESIS CYCLIZATION DIABETES MELLITUS DRUG DEVELOPMENT DRUG SYNTHESIS GLUCOSE ABSORPTION GLUCOSE METABOLISM HUMAN HYPERGLYCEMIA IC50 METABOLIC DISORDER NEUROPROTECTION REVIEW SIGNAL TRANSDUCTION |
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| Описание |
Natural products are a boundless source for the development of pharmaceutical agents against a wide range of human diseases. Accordingly, naturally occurring aurones possess various biological benefits, such as anticancer, antioxidant, antimicrobial, antidiabetic, anti-inflammatory, antiviral and neuroprotective effects. In addition, various studies have revealed that aurones are potential templates for the regulation of diabetes mellitus and its associated complications. Likewise, certain aurones and their analogues have been found to be remarkable kinase inhibitors of DARK2, PPAR-γ, PTPM1, AGE, α-amylase and α-glucosidase, which represents a promising approach for the treatment of chronic metabolic disorders such as diabetes. Therefore, in our present study, we provide a detailed account of the advances in aurones as antidiabetic agents over the past decade. © 2023 by the authors.
Ministry of Education and Science of the Russian Federation, Minobrnauka This research was funded by the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program). |
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| Дата |
2024-04-05T16:35:09Z
2024-04-05T16:35:09Z 2023 |
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| Тип |
Review
Review (info:eu-repo/semantics/review) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Aluru, R, Mukherjee, A, Zyryanov, G, Majee, A & Santra, S 2023, 'Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones', Current Issues in Molecular Biology, Том. 45, № 10, стр. 8461-8475. https://doi.org/10.3390/cimb45100533
Aluru, R., Mukherjee, A., Zyryanov, G., Majee, A., & Santra, S. (2023). Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones. Current Issues in Molecular Biology, 45(10), 8461-8475. https://doi.org/10.3390/cimb45100533 1467-3037 Final All Open Access, Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175087801&doi=10.3390%2fcimb45100533&partnerID=40&md5=252b8eb5e8dd2820b558c690dfc0ff95 https://www.mdpi.com/1467-3045/45/10/533/pdf?version=1697692167 http://elar.urfu.ru/handle/10995/130896 10.3390/cimb45100533 85175087801 001098241800001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
Multidisciplinary Digital Publishing Institute (MDPI)
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| Источник |
Current Issues in Molecular Biology
Current Issues in Molecular Biology |
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