Non-Polio Enterovirus Surveillance in the Ural Federal District and Western Siberia, 2022: Is There a Need for a Vaccine?
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Non-Polio Enterovirus Surveillance in the Ural Federal District and Western Siberia, 2022: Is There a Need for a Vaccine?
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| Автор |
Itani, T. M.
Chalapa, V. I. Slautin, V. N. Bykov, R. O. Imangaliev, B. S. Starikova, P. K. Sergeev, A. G. Semenov, A. V. |
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| Тематика |
CIRCULATION
COXSACKIE A6 ENTEROVIRAL MENINGITIS ENTEROVIUS TYPES EPIDEMIOLOGICAL SURVEILLANCE HAND-FOOT-AND-MOUTH DISEASE HERPANGINA NON-POLIO ENTEROVIRUS VACCINE NON-POLIO ENTEROVIRUSES PREVENTION POLIOMYELITIS VACCINE PROTEIN VP1 ADOLESCENT ADULT ARTICLE ASEPTIC MENINGITIS CEREBROSPINAL FLUID CHILD CORONAVIRUS DISEASE 2019 DISEASE SURVEILLANCE ENTEROVIRUS MENINGITIS EPIDEMIOLOGICAL SURVEILLANCE FEMALE GENOTYPE GENOTYPING HAND FOOT AND MOUTH DISEASE HERPANGINA HUMAN MAJOR CLINICAL STUDY MALE MENINGOENCEPHALITIS NASOPHARYNGEAL SWAB OROPHARYNGEAL SWAB PANDEMIC PHYLOGENETIC TREE POLIOMYELITIS POLIOMYELITIS VIRUS POLYMERASE CHAIN REACTION REAL TIME REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION RETROSPECTIVE STUDY RNA EXTRACTION SEMI-NESTED POLYMERASE CHAIN REACTION VESICULAR STOMATITIS |
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| Описание |
Human non-polio enteroviruses (NPEVs) are the etiological agents involved in most cases of hand-foot-and-mouth disease (HFMD), herpangina and aseptic meningitis. Information on the epidemiology profiles of NPEV in the Ural Federal District and Western Siberia is very limited, with no published data available. The aim of this study is to describe NPEV incidence in the Ural Federal District and Western Siberia among patients with different forms of non-polio enterovirus infections (NPEVIs) during 2022, stratified by age and clinical manifestations. A total of 265 samples that tested positive for NPEV using a polymerase chain reaction (PCR) were genotyped by semi-nested PCR for the VP1 gene. The results showed that 21 genotypes were identified among patients in this study. CVA6 was the most common genotype for HFMD. CVA6, along with CVA10, accounted for the majority of herpangina cases, while CVA9 was implicated in most meningitis cases. Sequence and phylogenetic analysis showed that nearly all of the CVA6 strains identified in this study displayed a close genetic relationship to strains identified in other cities in Russia and strains from China. NPEV surveillance allows for monitoring the circulation of clinically relevant genotypes, resulting in continuous data about NPEV epidemiology. This is important for improving case prevention, diagnosis and guiding clinical management. © 2023 by the authors.
121041500041-1 This research was funded by the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (scientific study № 121041500041-1). |
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| Дата |
2024-04-05T16:35:15Z
2024-04-05T16:35:15Z 2023 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
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| Идентификатор |
Itani, TM, Chalapa, VI, Slautin, VN, Bykov, RO, Imangaliev, BS, Starikova, PK, Sergeev, AG & Semenov, AV 2023, 'Non-Polio Enterovirus Surveillance in the Ural Federal District and Western Siberia, 2022: Is There a Need for a Vaccine?', Vaccines, Том. 11, № 10, 1588. https://doi.org/10.3390/vaccines11101588
Itani, T. M., Chalapa, V. I., Slautin, V. N., Bykov, R. O., Imangaliev, B. S., Starikova, P. K., Sergeev, A. G., & Semenov, A. V. (2023). Non-Polio Enterovirus Surveillance in the Ural Federal District and Western Siberia, 2022: Is There a Need for a Vaccine? Vaccines, 11(10), [1588]. https://doi.org/10.3390/vaccines11101588 2076-393X Final All Open Access, Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85175320471&doi=10.3390%2fvaccines11101588&partnerID=40&md5=bf5f92a1339ef62e39cd36f5cec133e2 https://www.mdpi.com/2076-393X/11/10/1588/pdf?version=1697105969 http://elar.urfu.ru/handle/10995/130904 10.3390/vaccines11101588 85175320471 001089544900001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
Multidisciplinary Digital Publishing Institute (MDPI)
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| Источник |
Vaccines
Vaccines |
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