Structural and Morphological Features of Anisotropic Chitosan Hydrogels Obtained by Ion-Induced Neutralization in a Triethanolamine Medium
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Structural and Morphological Features of Anisotropic Chitosan Hydrogels Obtained by Ion-Induced Neutralization in a Triethanolamine Medium
|
|
| Автор |
Shmakov, S. L.
Babicheva, T. S. Kurochkina, V. A. Lugovitskaya, T. N. Shipovskaya, A. B. |
|
| Тематика |
ANISOTROPIC HYDROGELS
BIOCOMPATIBLE POLYMERS CHITOSAN GLYCOLIC ACID LIESEGANG STRUCTURES TRIETHANOLAMINE |
|
| Описание |
For the first time, anisotropic hydrogel material with a highly oriented structure was obtained by the chemical reaction of polymer-analogous transformation of chitosan glycolate—chitosan base using triethanolamine (TEA) as a neutralizing reagent. Tangential bands or concentric rings, depending on the reaction conditions, represent the structural anisotropy of the hydrogel. The formation kinetics and the ratio of the positions of these periodic structures are described by the Liesegang regularities. Detailed information about the bands is given (formation time, coordinate, width, height, and formation rate). The supramolecular ordering anisotropy of the resulting material was evaluated both by the number of Liesegang bands (up to 16) and by the average values of the TEA diffusion coefficient ((15–153) × 10−10 and (4–33) × 10−10 m2/s), corresponding to the initial and final phase of the experiment, respectively. The minimum chitosan concentration required to form a spatial gel network and, accordingly, a layered anisotropic structure was estimated as 1.5 g/dL. Morphological features of the structural anisotropic ordering of chitosan Liesegang structures are visualized by scanning electron microscopy. The hemocompatibility of the material obtained was tested, and its high sorption–desorption properties were evaluated using the example of loading–release of cholecalciferol (loading degree ~35–45%, 100% desorption within 25–28 h), which was observed for a hydrophobic substance inside a chitosan-based material for the first time. © 2023 by the authors.
Russian Science Foundation, RSF: 22-23-00320 The study was supported by a grant from the Russian Science Foundation № 22-23-00320, https://rscf.ru/project/22-23-00320/, accessed on 3 November 2023. |
|
| Дата |
2024-04-05T16:36:58Z
2024-04-05T16:36:58Z 2023 |
|
| Тип |
Article
Journal article (info:eu-repo/semantics/article) |info:eu-repo/semantics/publishedVersion |
|
| Идентификатор |
Shmakov, SL, Babicheva, TS, Kurochkina, VA, Lugovitskaya, TN & Shipovskaya, AB 2023, 'Structural and Morphological Features of Anisotropic Chitosan Hydrogels Obtained by Ion-Induced Neutralization in a Triethanolamine Medium', Gels, Том. 9, № 11, 876. https://doi.org/10.3390/gels9110876
Shmakov, S. L., Babicheva, T. S., Kurochkina, V. A., Lugovitskaya, T. N., & Shipovskaya, A. B. (2023). Structural and Morphological Features of Anisotropic Chitosan Hydrogels Obtained by Ion-Induced Neutralization in a Triethanolamine Medium. Gels, 9(11), [876]. https://doi.org/10.3390/gels9110876 2310-2861 Final All Open Access, Gold, Green https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178120581&doi=10.3390%2fgels9110876&partnerID=40&md5=20c6c20a43ce2b2f8692ea168be8532e https://www.mdpi.com/2310-2861/9/11/876/pdf?version=1699093361 http://elar.urfu.ru/handle/10995/131000 10.3390/gels9110876 85178120581 001114639500001 |
|
| Язык |
en
|
|
| Связанные ресурсы |
info:eu-repo/grantAgreement/RSF//22-23-00320
|
|
| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
|
| Формат |
application/pdf
|
|
| Издатель |
Multidisciplinary Digital Publishing Institute (MDPI)
|
|
| Источник |
Gels
Gels |
|