Measurement of Mass Transfer Intensity in Gas–Liquid Medium of Bioreactor Circuit Using the Thermometry Method
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Measurement of Mass Transfer Intensity in Gas–Liquid Medium of Bioreactor Circuit Using the Thermometry Method
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| Автор |
Starodumov, I.
Nizovtseva, I. Lezhnin, S. Vikharev, S. Svitich, V. Mikushin, P. Alexandrov, D. Kuznetsov, N. Chernushkin, D. |
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| Тематика |
BIOREACTOR
FERMENTATION GAS–LIQUID FLOW JET FERMENTER KLA MASS TRANSFER COEFFICIENT MULTIPHASE FLOWS NUMERICAL MODELING SCALE-UP THERMOMETRY METHOD TWO-PHASE MEDIA |
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| Описание |
The development of energy-efficient solutions for large-scale fermenters demands a deep and comprehensive understanding of hydrodynamic and heat and mass transfer processes. Despite a wide variety of research dedicated to measurements of mass transfer intensity in bubble flows, this research subject faces new challenges due to the topical development of new innovative bioreactor designs. In order to understand the fluid dynamics of the gas–liquid medium, researchers need to develop verified CFD models describing flows in the bioreactor loop using a progressive physical and mathematical apparatus. In the current paper, we represent the results of evaluating the key performance indicator of the bioreactor, namely the volumetric mass transfer coefficient ((Formula presented.)) known as a parameter of dominant importance for the design, operation, scale-up, and optimization of bioreactors, using the developed thermometry method. The thermometry method under consideration was examined within a series of experiments, and a comparative analysis was provided for a number of various regimes also being matched with the classical approaches. The methodology, experiment results, and data verification are given, which allow the evaluation of the effectiveness and prediction of the fluid flows dynamics in bioreactors circuits and ultimately the operational capabilities of the fermenter line. © 2022 by the authors.
Ministry of Education and Science of the Russian Federation, Minobrnauka The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program) is gratefully acknowledged. |
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| Дата |
2024-04-08T11:05:37Z
2024-04-08T11:05:37Z 2022 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) Published version (info:eu-repo/semantics/publishedVersion) |
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| Идентификатор |
Starodumov, I, Nizovtseva, I, Lezhnin, S, Vikharev, S, Svitich, V, Mikushin, P, Alexandrov, D, Kuznetsov, N & Chernushkin, D 2022, 'Measurement of Mass Transfer Intensity in Gas–Liquid Medium of Bioreactor Circuit Using the Thermometry Method', Fluids, Том. 7, № 12, 366. https://doi.org/10.3390/fluids7120366
Starodumov, I., Nizovtseva, I., Lezhnin, S., Vikharev, S., Svitich, V., Mikushin, P., Alexandrov, D., Kuznetsov, N., & Chernushkin, D. (2022). Measurement of Mass Transfer Intensity in Gas–Liquid Medium of Bioreactor Circuit Using the Thermometry Method. Fluids, 7(12), [366]. https://doi.org/10.3390/fluids7120366 2311-5521 Final All Open Access; Gold Open Access https://www.mdpi.com/2311-5521/7/12/366/pdf?version=1669543986 https://www.mdpi.com/2311-5521/7/12/366/pdf?version=1669543986 http://elar.urfu.ru/handle/10995/131186 10.3390/fluids7120366 85144692045 000902493600001 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
MDPI
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| Источник |
Fluids
Fluids |
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