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Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate

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Заглавие Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate
 
Автор Kochnev, I. A.
Barkov, A. Y.
Zimnitskiy, N. S.
Korotaev, V. Y.
Sosnovskikh, V. Y.
 
Тематика 2,4-DIHYDROCHROMENO[3,4-C]PYRROLES
3-NITRO-2H-CHROMENES
BARTON–ZARD REACTION
ETHYL ISOCYANOACETATE
 
Описание A regioselective one-pot method for the synthesis of 1-ethyl 2,4-dihydrochromene[3,4-c]pyrroles in 63–94% yields from available 2-phenyl-, 2-trifluoro(trichloro)methyl- or 2-phenyl-2-(trifluoromethyl)-3-nitro-2H-chromenes and ethyl isocyanoacetate through the Barton–Zard reaction in ethanol at reflux for 0.5 h, using K2CO3 as a base, has been developed. © 2022 by the authors.
Russian Foundation for Basic Research, РФФИ, (20-03-00716)
Ministry of Education and Science of the Russian Federation, Minobrnauka, (FEUZ-2020-0052)
This research was funded by the Russian Foundation for Basic Research (project 20-03-00716) and the Ministry of Science and Higher Education of the Russian Federation (project FEUZ-2020-0052).
 
Дата 2024-04-08T11:06:40Z
2024-04-08T11:06:40Z
2022
 
Тип Article
Journal article (info:eu-repo/semantics/article)
Published version (info:eu-repo/semantics/publishedVersion)
 
Идентификатор Kochnev, IA, Barkov, AY, Zimnitskiy, NS, Korotaev, VY & Sosnovskikh, VY 2022, 'Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate', Molecules, Том. 27, № 23, 8456. https://doi.org/10.3390/molecules27238456
Kochnev, I. A., Barkov, A. Y., Zimnitskiy, N. S., Korotaev, V. Y., & Sosnovskikh, V. Y. (2022). Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate. Molecules, 27(23), [8456]. https://doi.org/10.3390/molecules27238456
1420-3049
Final
All Open Access; Gold Open Access; Green Open Access
https://www.mdpi.com/1420-3049/27/23/8456/pdf?version=1669979105
https://www.mdpi.com/1420-3049/27/23/8456/pdf?version=1669979105
http://elar.urfu.ru/handle/10995/131332
10.3390/molecules27238456
85143716450
000897258800001
 
Язык en
 
Права Open access (info:eu-repo/semantics/openAccess)
cc-by
https://creativecommons.org/licenses/by/4.0/
 
Формат application/pdf
 
Издатель MDPI
 
Источник Molecules
Molecules