Biomimetic Mineralization of Tooth Enamel Using Nanocrystalline Hydroxyapatite under Various Dental Surface Pretreatment Conditions
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Biomimetic Mineralization of Tooth Enamel Using Nanocrystalline Hydroxyapatite under Various Dental Surface Pretreatment Conditions
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| Автор |
Seredin, P.
Goloshchapov, D. Kashkarov, V. Emelyanova, A. Buylov, N. Barkov, K. Ippolitov, Y. Khmelevskaia, T. Mahdy, I. A. Mahdy, M. A. Prutskij, T. |
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| Тематика |
AFM
BIOMIMETIC ENAMEL TISSUE FESEM MINERALIZATION NANOINDENTATION RAMAN SPECTROMICROSCOPY XRD |
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| Описание |
In this report, we demonstrated the formation of a biomimetic mineralizing layer obtained on the surface of dental enamel (biotemplate) using bioinspired nanocrystalline carbonate-substituted calcium hydroxyapatite (ncHAp), whose physical and chemical properties are closest to the natural apatite dental matrix, together with a complex of polyfunctional organic and polar amino acids. Using a set of structural, spectroscopy, and advanced microscopy techniques, we confirmed the formation of a nanosized ncHAp-based mineralized layer, as well as studying its chemical, substructural, and morphological features by means of various methods for the pretreatment of dental enamel. The pretreatment of a biotemplate in an alkaline solution of Ca(OH)2 and an amino acid booster, together with the executed subsequent mineralization with ncHAp, led to the formation of a mineralized layer with homogeneous micromorphology and the preferential orientation of the ncHAp nanocrystals. It was shown that the homogeneous crystallization of hydroxyapatite on the biotemplate surface and binding of individual nanocrystals and agglomerates into a single complex by an amino acid booster resulted in an increase (~15%) in the nanohardness value in the enamel rods area, compared to that of healthy natural enamel. Obtaining a similar hierarchy and cleavage characteristics as natural enamel in the mineralized layer, taking into account the micromorphological features of dental tissue, is an urgent problem for future research. © 2022 by the authors.
Russian Science Foundation, RSF, (21-75-10005) Ministry of Science and Higher Education of the Russian Federation, (N 075-15-2021-1351) This work was funded by the Russian Science Foundation, under grant number 21-75-10005. Access to scientific equipment and methodologies was provided via support from the Ministry of Science and Higher Education of Russia, under agreement N 075-15-2021-1351. |
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| Дата |
2024-04-08T11:07:05Z
2024-04-08T11:07:05Z 2022 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) Published version (info:eu-repo/semantics/publishedVersion) |
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| Идентификатор |
Seredin, P, Goloshchapov, D, Kashkarov, V, Emelyanova, A, Buylov, N, Barkov, K, Ippolitov, Y, Khmelevskaia, T, Mahdy, IA, Mahdy, MA & Prutskij, T 2022, 'Biomimetic Mineralization of Tooth Enamel Using Nanocrystalline Hydroxyapatite under Various Dental Surface Pretreatment Conditions', Biomimetics, Том. 7, № 3, 111, стр. 111. https://doi.org/10.3390/biomimetics7030111
Seredin, P., Goloshchapov, D., Kashkarov, V., Emelyanova, A., Buylov, N., Barkov, K., Ippolitov, Y., Khmelevskaia, T., Mahdy, I. A., Mahdy, M. A., & Prutskij, T. (2022). Biomimetic Mineralization of Tooth Enamel Using Nanocrystalline Hydroxyapatite under Various Dental Surface Pretreatment Conditions. Biomimetics, 7(3), 111. [111]. https://doi.org/10.3390/biomimetics7030111 2313-7673 Final All Open Access; Gold Open Access; Green Open Access https://www.mdpi.com/2313-7673/7/3/111/pdf?version=1660287793 https://www.mdpi.com/2313-7673/7/3/111/pdf?version=1660287793 http://elar.urfu.ru/handle/10995/131402 10.3390/biomimetics7030111 85138607248 000858099400001 |
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| Язык |
en
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| Связанные ресурсы |
info:eu-repo/grantAgreement/RSF//21-75-10005
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by https://creativecommons.org/licenses/by/4.0/ |
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| Формат |
application/pdf
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| Издатель |
MDPI
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| Источник |
Biomimetics
Biomimetics |
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