Exploring CNS Effects of American Traditional Medicines using Zebrafish Models
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
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Exploring CNS Effects of American Traditional Medicines using Zebrafish Models
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| Автор |
de Abreu, M. S.
Costa, F. Giacomini, A. C. V. V. Demin, K. A. Petersen, E. V. Rosemberg, D. B. Kalueff, A. V. |
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| Тематика |
AMERICAN TRADITIONAL MEDICINE
ANIMAL MODELS BEHAVIOR BRAIN EFFECTS DRUG SCREENING ZEBRAFISH ANIMALS DISEASE MODELS, ANIMAL MEDICINE, TRADITIONAL NEUROPHARMACOLOGY NEUROSCIENCES ZEBRAFISH DIZOCILPINE N METHYL DEXTRO ASPARTIC ACID 4 AMINOBUTYRIC ACID BRAIN LEVEL AMERICAN TRADITIONAL MEDICINE BRAIN DISEASE CENTRAL NERVOUS SYSTEM GLUTAMATERGIC TRANSMISSION NONHUMAN REVIEW TRADITIONAL MEDICINE ANIMAL DISEASE MODEL NEUROPHARMACOLOGY NEUROSCIENCE ZEBRA FISH |
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| Описание |
Although American traditional medicine (ATM) has been practiced for millennia, its complex multi-target mechanisms of therapeutic action remain poorly understood. Animal models are widely used to elucidate the therapeutic effects of various ATMs, including their modulation of brain and behavior. Complementing rodent models, the zebrafish (Danio rerio) is a promising novel organism in translational neuroscience and neuropharmacology research. Here, we emphasize the growing value of zebrafish for testing neurotropic effects of ATMs and outline future directions of research in this field. We also demonstrate the developing utility of zebrafish as complementary models for probing CNS mechanisms of ATM action and their potential to treat brain disorders. © 2022 Bentham Science Publishers.
Applied Genetics MIPT, (075-15-2021-684) International Zebrafish Neurosci-ence Research Consortium Sirius University Southwest University Zebrafish Platform Construction Funds (Chongqing, China ZNRC Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, (305051/2018-0) Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, FAPERGS, (19/2551-0001-669-7, 19/2551-0001764-2) Russian Science Foundation, RSF, (20-65-46006) The study is supported by the Southwest University Zebrafish Platform Construction Funds (Chongqing, China). AVK is the Chair of the International Zebrafish Neurosci-ence Research Consortium (ZNRC) that coordinated this collaborative project. DBR receives the CNPq research productivity grant (process 305051/2018-0) and the FAPERGS “Gaucho” Researcher Program – PQG fellowship grant (process 19/2551-0001764-2). ACVVG is supported by the FAPERGS research fellowships 19/2551-0001-669-7. The study is partly supported by Sirius University (Sochi, Russia). Research collaboration here is supported by the Russian Science Foundation (RSF) grant 20-65-46006 to Prof. T.G. Amstislavskaya. The funders had no role in the design, analyses, and interpretation of the submitted study or the decision to publish. The study used the facilities and equipment of the Resource Fund of Applied Genetics MIPT (support grant 075-15-2021-684). |
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| Дата |
2024-04-22T15:53:37Z
2024-04-22T15:53:37Z 2022 |
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| Тип |
Review
Review (info:eu-repo/semantics/review) Published version (info:eu-repo/semantics/publishedVersion) |
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| Идентификатор |
de Abreu, MS, Costa, F, Giacomini, ACVV, Demin, KA, Petersen, EV, Rosemberg, DB & Kalueff, AV 2022, 'Exploring CNS Effects of American Traditional Medicines using Zebrafish Models', Current Neuropharmacology, Том. 20, № 3, стр. 550-559. https://doi.org/10.2174/1570159X19666210712153329
de Abreu, M. S., Costa, F., Giacomini, A. C. V. V., Demin, K. A., Petersen, E. V., Rosemberg, D. B., & Kalueff, A. V. (2022). Exploring CNS Effects of American Traditional Medicines using Zebrafish Models. Current Neuropharmacology, 20(3), 550-559. https://doi.org/10.2174/1570159X19666210712153329 1570-159X Final All Open Access; Green Open Access https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608231 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608231 http://elar.urfu.ru/handle/10995/132468 10.2174/1570159X19666210712153329 85126830478 811614400008 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
cc-by |
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| Формат |
application/pdf
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| Издатель |
Bentham Science Publishers
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| Источник |
Current Neuropharmacology
Current Neuropharmacology |
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