Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins
Электронный научный архив УРФУ
Информация об архиве | Просмотр оригинала| Поле | Значение | |
| Заглавие |
Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins
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| Автор |
Rusinov, V. L.
Sapozhnikova, I. M. Ulomskii, E. N. Medvedeva, N. R. Egorov, V. V. Kiselev, O. I. Deeva, E. G. Vasin, A. V. Chupakhin, O. N. |
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| Тематика |
AZOLO[5,1-C]TRIAZINES
CYSTEINE GLUTATHIONE METABOLIC TRANSFORMATIONS NITRO COMPOUNDS NUCLEOPHILIC SUBSTITUTION TRIAZAVIRIN |
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| Описание |
[Figure not available: see fulltext.] The nucleophilic susbstitution of nitro group in [1,2,4]triazolo[5,1-c][1,2,4]triazinones upon treatment with cysteine and glutathione was studied as a model for the interaction with thiol groups of virus proteins, which mimics the metabolic transformations of antiviral drug Triazavirin® and its derivatives. © 2015 Springer Science+Business Media New York.
Russian Science Foundation, RSF: 14-13-01301 The study was performed with the financial support from the Russian Science Foundation (grant 14-13-01301). |
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| Дата |
2024-04-22T18:30:04Z
2024-04-22T18:30:04Z 2015 |
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| Тип |
Article
Journal article (info:eu-repo/semantics/article) Published version (info:eu-repo/semantics/publishedVersion) |
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| Идентификатор |
Rusinov, V. L. et al. (2015) ‘Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins’, Chemistry of heterocyclic compounds. Springer Science and Business Media LLC, 51(3), pp. 275–280. doi: 10.1007/s10593-015-1695-4.
Rusinov, V. L., Sapozhnikova, I. M., Ulomskii, E. N., Medvedeva, N. R., Egorov, V. V., Kiselev, O. I., … Chupakhin, O. N. (2015). Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins. Chemistry of Heterocyclic Compounds, 51(3), 275–280. doi:10.1007/s10593-015-1695-4 0009-3122 Final All Open Access, Bronze https://link.springer.com/content/pdf/10.1007/s10593-015-1695-4.pdf http://elar.urfu.ru/handle/10995/132506 10.1007/s10593-015-1695-4 84953354086 000354479700011 |
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| Язык |
en
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| Права |
Open access (info:eu-repo/semantics/openAccess)
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| Формат |
application/pdf
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| Издатель |
Springer New York LLC
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| Источник |
Chemistry of Heterocyclic Compounds
Chemistry of Heterocyclic Compounds |
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